Key result
False LBBB morphology was associated with a higher risk of all-cause mortality and heart failure hospitalization compared to true LBBB in patients receiving CRT (HR 3.98; 95% CI 1.51-10.48).
Why the study?
Does "true" LBBB morphology predict a better clinical and echocardiographic response to CRT compared to "false" LBBB in patients with LVEF ≤ 35%?
Cohort (n=111)
Does "true" LBBB morphology predict a better clinical and echocardiographic response to CRT compared to "false" LBBB in patients with LVEF ≤ 35%?
Hazard Ratio: 3.98 (95% CI 1.51–10.48)
Electrocardiographic criteria for "true" LBBB morphology can identify patients who will have a better clinical and echocardiographic response to cardiac resynchronization therapy.
No takes yet. Share an insight, caveat, or question.
Stricter LBBB criteria may aid CRT selection; hypothesis-generating in observational data, prospective trials needed.
Mascioli et al. (2012) conducted a cohort in Severe congestive heart failure (n=111). False LBBB morphology vs. True LBBB morphology was evaluated on Composite of all-cause mortality and hospital admission with heart failure (HR 3.98, 95% CI 1.51-10.48). False LBBB morphology was associated with a higher risk of all-cause mortality and heart failure hospitalization compared to true LBBB in patients receiving CRT (HR 3.98; 95% CI 1.51-10.48).
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