Key result
True left bundle branch block morphology was a strong independent predictor of super-response to cardiac resynchronization therapy (OR 11.680; 95% CI 1.966-69.390; P=0.007).
Why the study?
Does true LBBB morphology (with mid-QRS notching/slurring) predict a better response to cardiac resynchronization therapy compared to non-true LBBB or IVCD in patients with congestive heart failure?
Population
n=58 patients with congestive heart failure prospectively enrolled and categorized into three groups based…
Comparison
Cardiac resynchronization therapy in patients… vs Cardiac resynchronization therapy in patients…
Design
Cohort
Follow-up
6 months
Authors
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May aid CRT candidate selection; hypothesis-generating from observational data and needs prospective validation.
Cohort (n=58)
Does true LBBB morphology (with mid-QRS notching/slurring) predict a better response to cardiac resynchronization therapy compared to non-true LBBB or IVCD in patients with congestive heart failure?
Odds Ratio: 11.68 (95% CI 1.966–69.39)
p-value: p=0.007
In patients receiving CRT, the presence of true LBBB morphology (defined by mid-QRS notching or slurring) strongly predicts a superior echocardiographic and clinical response compared to non-true LBBB or IVCD.
Tian et al. (2013) conducted a cohort in Congestive heart failure (n=58). True left bundle branch block (t-LBBB) morphology vs. Non-true LBBB and non-specific intraventricular conduction delay was evaluated on Super-response to cardiac resynchronization therapy (OR 11.680, 95% CI 1.966-69.390, p=0.007). True left bundle branch block morphology was a strong independent predictor of super-response to cardiac resynchronization therapy (OR 11.680; 95% CI 1.966-69.390; P=0.007).
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