March 4, 2014European Heart Journal Acute Cardiovascular Care
Temporal trends in epidemiology, clinical presentation and management of acute heart failure: results from the Greek cohorts of the Acute Heart Failure Global Registry of Standard Treatment and the European Society of Cardiology-Heart Failure pilot survey
Key result
Temporal trends in acute heart failure management in Greece showed an increase in guideline-recommended therapies and a drop in in-hospital mortality from 8.5% in 2006-2007 to 4.5% in 2009-2010.
Population
432 acute heart failure patients recruited by Greek sites in two registries, comprising ~60% acutely…
Design
Cohort
Follow-up
in-hospital
Authors
Discussion
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Member takes
Implication
Supports GDMT uptake in acute HF; hypothesis-generating without causal confirmation from observational data.
Study Design
Type
Observational (n=432)
Multicenter
Yes
Structured PICO
P
Population
432 acute heart failure (AHF) patients recruited by Greek sites in two registries (255 in ALARM-HF during 2006-2007 and 177 in ESC-HF pilot survey during 2009-2010), comprising ~60% acutely decompensated chronic HF and ~40% de novo AHF.
O
Outcome
Changes in epidemiology, clinical presentation, and management of AHF, including in-hospital mortality and length of hospitalisationhard clinical
Main Result
Absolute Event Rate: 4.5% vs 8.5%
Between 2006 and 2010 in Greece, the use of guideline-directed medical therapy for acute heart failure increased significantly, corresponding with a reduction in in-hospital mortality.
Cite This Study
Filippatos et al. (2014) conducted an observational in Acute heart failure (n=432). ESC-HF pilot survey (2009-2010) vs. ALARM-HF registry (2006-2007) was evaluated on In-hospital mortality. Temporal trends in acute heart failure management in Greece showed an increase in guideline-recommended therapies and a drop in in-hospital mortality from 8.5% in 2006-2007 to 4.5% in 2009-2010.