Key result
Dynamic ECG links CHD and heart failure to ~24% lower QRS voltage and prolonged QTc.
Why the study?
This study evaluated the efficacy of dynamic electrocardiogram parameters for predicting coronary artery lesions in patients with coronary heart disease and heart failure.
Can dynamic electrocardiogram parameters predict the presence and severity of coronary artery lesions in patients with coronary heart disease and heart failure?
Case-Control (n=300)
No
Can dynamic electrocardiogram parameters predict the presence and severity of coronary artery lesions in patients with coronary heart disease and heart failure?
Dynamic electrocardiogram parameters such as QRS voltage, QTc interval, and QRS duration can serve as noninvasive markers for predicting the severity of coronary artery lesions in patients with coronary heart disease and heart failure.
Answers are grounded in this paper and cite their sources.
May support dynamic ECG parameters as noninvasive markers in CHD with HF; hypothesis-generating, requires prospective validation.
To analyze the application efficiency of dynamic electrocardiogram in predicting coronary artery lesions in patients with coronary heart disease and heart failure.Methods150 patients with coronary heart disease and heart failure who were examined in the ECG Diagnosis Department of Yichang Central People's Hospital from July 2024 to December 2025 were selected as the research group, and 150 volunteers who were examined in the hospital during the same period were selected as the control group. Both groups were examined by dynamic electrocardiogram. The ECG parameters of patients with single or multiple coronary artery disease in the two groups and the observation group were compared, and the relationship between coronary artery disease and ECG was analyzed.ResultsThe QRS voltage in the study group was significantly lower than that in the control group, and the QTc interval and QRS time limit were significantly higher than that in the control group (P < 0.001). The QRS voltage of patients with multi-vessel coronary artery disease in the study group was significantly lower than that of patients with single vessel disease, and the QTc interval and QRS time limit were significantly higher than that of patients with single vessel disease (P < 0.001). There is a significant correlation between coronary artery disease and the parameters of dynamic electrocardiogram. QRS voltage is negatively correlated with the degree of disease, while QTc interval and QRS time limit are positively correlated with the degree of disease.ConclusionQRS voltage, QTc interval and QRS time limit of dynamic electrocardiogram can effectively distinguish patients with coronary heart disease and heart failure from healthy people, and are closely related to the severity of coronary artery disease, which can be used as a noninvasive and convenient reference index for clinical prediction of coronary artery disease in patients with coronary heart disease and heart failure.
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Zhao YanHua (2026) conducted a case-control in Coronary heart disease and heart failure (n=300). Dynamic electrocardiogram vs. Healthy volunteers was evaluated on QRS voltage (mV) (p=<0.001). Dynamic electrocardiogram revealed significantly lower QRS voltage and prolonged QTc interval and QRS duration in patients with coronary heart disease and heart failure compared to healthy controls.
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