Why the study?
Do patients with acute leukaemia and lymphoma have left ventricular dysfunction prior to and following chemotherapy?
Population
38 patients with acute leukaemia and lymphoma, and 27 normal subjects (total n=65).
Comparison
Echocardiographic assessment (observational). vs Normal subjects (n=27).
Design
Cohort
Follow-up
>9 months
Authors
Loading...
Pre-treatment LV assessment may be considered in leukaemia-lymphoma; this Level 3 evidence leaves open disease-related mechanisms and requires prospective confirmation.
Do patients with acute leukaemia and lymphoma have left ventricular dysfunction prior to and following chemotherapy?
A significant proportion of patients with acute leukaemia and lymphoma exhibit non-infiltrative left ventricular dysfunction even before receiving cardiotoxic chemotherapy.
Mariam Mir (1978) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: