Leukaemic myocardial infiltration presenting as acute heart failure
Key result
Chemotherapy and medical therapy completely resolve acute heart failure driven by leukaemic myocardial infiltration.
- n=1
Population
1 34-year-old man with M5b acute monocytic leukaemia associated with hyperleukocytosis presenting with acute…
Design
Case_report
Follow-up
2 weeks after completion of chemotherapy
Authors
Discussion
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Member takes
Implication
Alerts clinicians to reversible leukaemic infiltration as rare acute HF cause; extends sparse case evidence for imaging in leukaemia.
Study Design
Type
Case Report (n=1)
Structured PICO
P
Population
A 34-year-old man with M5b acute monocytic leukaemia who developed acute heart failure due to leukaemic myocardial infiltration.
I
Intervention
Induction chemotherapy with 7+3 IDAC (cytarabin plus idarubicin) protocol, along with furosemide and bisoprolol.
O
Outcome
Improvement in acute heart failure symptoms and normalization of echocardiographic findings (left ventricular wall thickness, echogenicity, and pericardial effusion).surrogate
Cardiovascular imaging is essential for diagnosing and managing reversible leukaemic myocardial infiltration presenting as acute heart failure.
Cite This Study
Silva et al. (2014) conducted a case report in M5b acute monocytic leukaemia with acute heart failure (n=1). Chemotherapy (cytarabin plus idarubicin) and heart failure therapy was evaluated. A 34-year-old man with acute monocytic leukaemia developed acute heart failure due to leukaemic myocardial infiltration, which completely resolved after chemotherapy and heart failure treatment.