Chemotherapy and pericardial drainage can lead to complete regression of massive cardiac involvement in patients with acute T cell leukemia.
Answers are grounded in this paper and cite their sources.
Supports combined drainage and chemotherapy for rare cardiac leukemia involvement; leaves open durability and generalizability.
Adult T cell leukemia/lymphomas are aggressive disorders, which infiltrate not only the bone marrow but extensively the visceral organs as well. A case with left ventricular systolic dysfunction with myocardial infiltration and massive pericardial effusion which was demonstrated with echocardiography is discussed. The patient responded well to pericardial drainage and subsequent chemotherapy. The dramatic improvement in echocardiographic findings after chemotherapy gave a clue to investigate suspected patients with aggressive leukemia and lymphomas for exclusion of leukemic infiltration of myocardium.
No takes yet. Share an insight, caveat, or question.
Arat et al. (2007) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: