Key result
Multimodality imaging guides pericardiocentesis draining >1,000 mL of hemorrhagic fluid in myo-pericardial leukemic infiltration.
Why the study?
Cardiac involvement in hematologic malignancies is uncommon and often subclinical, with limited data on multimodality imaging detection.
Population
1 patient with relapsed acute lymphoblastic leukemia and cardiac symptoms
Comparison
Multimodality imaging and pericardiocentesis for diagnosis
Design
Case report
Authors
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Cardiac infiltration warrants consideration in hypotensive relapsed leukemia; leaves open need for systematic screening protocols in prospective cohorts.
Case Report (n=1)
Multimodality imaging, particularly CMR, is pivotal for the non-invasive tissue characterization and diagnosis of cardio-pericardial infiltration in patients with hematologic malignancies.
Scollo et al. (2026) conducted a case report in Acute lymphoblastic leukemia with cardiac involvement (n=1). Multimodality imaging and pericardiocentesis was evaluated. Multimodality imaging identified myo-pericardial leukemic infiltration, guiding pericardiocentesis that drained >1,000 mL of hemorrhagic fluid in a 41-year-old man with relapsed ALL.
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