Key result
Breathing 100% oxygen versus air during hyperbaric dives fails to alter carotid body chemosensitivity.
Why the study?
Does breathing 100% oxygen versus air alter carotid body chemosensitivity to hypercapnia during a 4-h dive at 1.6 ATA?
Does breathing 100% oxygen versus air alter carotid body chemosensitivity to hypercapnia during a 4-h dive at 1.6 ATA?
Attenuation of carotid body chemosensitivity to hypercapnia does not contribute to CO2 retention in hyperbaria, as chemosensitivity remains unchanged regardless of breathing air or 100% oxygen at 1.6 ATA.
Attenuation of chemosensitivity does not contribute to CO2 retention in hyperbaria; leaves open alternative mechanisms for study.
We demonstrate that carotid body chemosensitivity to brief exposures of hypercapnia was unchanged during a 4-h dive in a dry hyperbaric chamber at 1.6 ATA regardless of breathing gas condition [i.e., air (21% O 2 ) versus 100% oxygen]. Therefore, it appears that an attenuation of carotid body chemosensitivity to hypercapnia does not contribute to CO 2 retention in hyperbaria.
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Hess et al. (2020) studied this question. Breathing air versus 100% oxygen during a 4-hour hyperbaric dive at 1.6 ATA did not alter carotid body chemosensitivity to hypercapnia.
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