What is the clinical evidence from this study?

Study design: Other. Primary outcome: Tissue-specific expression of AT1A and AT1B mRNA.

What does this research mean for the field?

AT1A and AT1B genes exhibit disparate tissue-specific expression profiles in mice, with AT1A widely expressed across tissues while AT1B is restricted to the brain, testes, and adrenal gland. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

August 1, 1994AJP Endocrinology and Metabolism

Differential expression of angiotensin receptor 1A and 1B in mouse

View Full Paper

Ask AI

Bookmark

Key result

AT1A and AT1B genes exhibit disparate tissue-specific expression profiles in mice, with AT1A widely expressed across tissues while AT1B is restricted to brain, testes, and adrenal gland.

Authors

JBJ M BursonUniversity of Iowa GAG. AguileraUniversity of Iowa KGKenneth W. GrossRoswell Park Comprehensive Cancer Center

Discussion

Member takes

Implication

Mouse AT1A/AT1B expression patterns should not guide human therapy; extends prior rodent studies by mapping subtype distribution.

PICO

Primary Outcome

Tissue-specific expression of AT1A and AT1B mRNA

Cite This Study

Burson et al. (1994) studied this question. AT1A and AT1B genes exhibit disparate tissue-specific expression profiles in mice, with AT1A widely expressed across tissues while AT1B is restricted to brain, testes, and adrenal gland.

synapsesocial.com/papers/6a16b4c64f6063e06b050cff https://doi.org/10.1152/ajpendo.1994.267.2.e260

View Full Paper

Ask AI

Bookmark

Differential expression of angiotensin receptor 1A and 1B in mouse

Discussion

Member takes

Implication

PICO

Cite This Study

Differential expression of angiotensin receptor 1A and 1B in mouse

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider