Key result
Male sex and the presence of clinical coronary heart disease were independent predictors of left ventricular akinesis or dyskinesis in elderly adults (both P<0.001).
Cohort (n=5,201)
Yes
p-value: p=<.001
In the elderly, male sex and prevalent coronary heart disease are strongly associated with increased left ventricular mass and systolic dysfunction on echocardiography.
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Should not yet change practice in elderly adults; leaves open causal links and need for longitudinal validation.
Gardin et al. (1995) conducted a cohort in Left ventricular hypertrophy and systolic dysfunction (n=5,201). Male sex and clinical coronary heart disease (observational exposures) vs. Female sex and absence of clinical heart disease was evaluated on Echocardiographic left ventricular mass and global/segmental systolic function (p=<.001). Male sex and the presence of clinical coronary heart disease were independent predictors of left ventricular akinesis or dyskinesis in elderly adults (both P<0.001).
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