Why the study?
Does the pressure-rate product predict myocardial oxygen demand in normal and hypertrophic right ventricles in dogs?
Population
28 open-chest dogs
Comparison
Increasing right ventricular myocardial oxygen… vs Normal right ventricle vs hypertrophic right…
Design
Preclinical
Follow-up
6 months (for RVH induction)
Authors
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Normalized PRP may predict RVMVO2 across canine RV phenotypes; leaves open human translation.
Does the pressure-rate product predict myocardial oxygen demand in normal and hypertrophic right ventricles in dogs?
The pressure-rate product, when normalized for wall thickness, can reliably predict myocardial oxygen demand in both normal and well-compensated hypertrophic right ventricles.
Saito et al. (1993) studied this question.