Key result
Pre-existing chronic heart failure in patients presenting with acute coronary syndrome was associated with significantly increased 6-month mortality (OR 2.25; 95% CI 1.55-3.27).
Why the study?
Does pre-existing chronic heart failure worsen outcomes in patients presenting with an acute coronary syndrome?
Population
5,556 patients presenting with an acute coronary syndrome enrolled in the Australia-New Zealand population…
Comparison
Pre-existing chronic heart failure (CHF) vs No pre-existing chronic heart failure
Design
Cohort
Follow-up
6 months
Authors
Loading...
Supports closer monitoring of ACS patients with prior HF; extends observational data but leaves causal inference and practice change open.
Observational (n=5,556)
Yes
Does pre-existing chronic heart failure worsen outcomes in patients presenting with an acute coronary syndrome?
Effect estimate: OR 2.25 (95% CI 1.55-3.27)
Patients with pre-existing chronic heart failure presenting with an acute coronary syndrome have significantly higher mortality and complication rates, although outcomes improved over a 9-year period alongside increased use of evidence-based therapies.
Ranasinghe et al. (2012) conducted an observational in Acute coronary syndrome with chronic heart failure (n=5,556). Pre-existing chronic heart failure vs. No chronic heart failure was evaluated on 6-month mortality (OR 2.25, 95% CI 1.55-3.27). Pre-existing chronic heart failure in patients presenting with acute coronary syndrome was associated with significantly increased 6-month mortality (OR 2.25; 95% CI 1.55-3.27).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: