Right ventricular diastolic pressure-volume relations and regional dimensions during acute alterations in loading conditions.

9 normal subjects

Intravenous phenylephrine (0.2 to 0.3 mg) and nitroprusside (0.5 to 1.5 micrograms/kg/min) to achieve three disparate peak right ventricular pressures, after partial autonomic blockade with atropine (1 mg) and propranolol (0.15 mg/kg)

Different loading conditions (low, medium, and high) within the same subjects

Right ventricular diastolic pressure-volume relationssurrogate