Key result
A CAVI value < 9 combined with an HDL-C level < 40 mg/dL identified individuals with a residual risk of experiencing a cardiovascular disease event among those at risk.
Why the study?
Does the combination of CAVI < 9 and HDL-C < 40 mg/dL identify residual risk of cardiovascular disease events in at-risk individuals?
Does the combination of CAVI < 9 and HDL-C < 40 mg/dL identify residual risk of cardiovascular disease events in at-risk individuals?
Answers are grounded in this paper and cite their sources.
Combining CAVI and HDL-C assessment helps identify residual cardiovascular risk in patients, as arterial stiffness is independent of blood pressure at the time of assessment.
Among individuals at risk for cardiovascular disease, the combination of a CAVI value < 9 and an HDL-C level < 40 mg/dL identified those with a residual risk of experiencing a cardiovascular disease event. Hypertension management alone does not completely alleviate the hemodynamic load imposed by arterial stiffness because CAVI is independent of blood pressure at the time of assessment.
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Li et al. (2026) studied this question. A CAVI value < 9 combined with an HDL-C level < 40 mg/dL identified individuals with a residual risk of experiencing a cardiovascular disease event among those at risk.
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