Key result
Pharmaceutical care provided by pharmacists significantly reduced systolic blood pressure by a mean difference of 12.24 mmHg compared to standard care in patients with essential hypertension.
Why the study?
Does pharmacist-led pharmaceutical care improve blood pressure control and quality of life in patients with essential hypertension?
RCT (n=142)
Block randomization
No
Does pharmacist-led pharmaceutical care improve blood pressure control and quality of life in patients with essential hypertension?
Effect estimate: Mean difference 12.24 mmHg
Absolute Event Rate: 132.5% vs 139.43%
p-value: p=0.0001
Pharmacist-led pharmaceutical care interventions significantly improve blood pressure control and health-related quality of life in patients with essential hypertension.
Supports pharmacist integration in hypertension care; leaves open randomized confirmation before practice change.
OBJECTIVE: The main objective of this study was to assess the effects of pharmaceutical care interventions in patients with essential hypertension in Lakshmi Pat Singhania Institute of Cardiology, Kanpur, India. METHODS: The study was carried out from July 2010 to August 2011. Pharmaceutical care was provided for 54 patients (intervention group) which was comprised of the patient education, the prescription assistance and the life style modifications and motivation for health. Then the clinical outcome as well as health related quality of life (HRQOL) were compared with the control group (48 patients) in which the pharmaceutical care was not provided. Furthermore, the effect of pharmaceutical care intervention on HRQOL was assessed using Short Form-36 (SF-36), a general health related quality of life questionnaire used to evaluate the QOL of patients. Blood pressure (BP) measurements and QOL survey was performed at baseline and at the follow-up session. FINDINGS: The difference between blood pressure readings from the baseline to the second follow-up was significant for systolic [(P = 0.0001), 12.24 mmHg] and diastolic BP [(P = 0.001), 5.17 mmHg] in the intervention group. The questionnaire used to evaluate the QOL of patients also showed improvement in the mean score for intervention group. CONCLUSION: Results from our study showed that applying pharmaceutical care to hypertensive patients can help in the control of these patients' blood pressure, and consequently lower the risk that hypertension poses in cardiovascular disease. Successful implementation of pharmaceutical care has the potential to increase patients' satisfaction with their pharmacists' activities and may increase patients' expectations that pharmacists will work on their behalf to assist them with their healthcare needs.
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Wal et al. (2013) conducted an RCT in Essential hypertension (n=142). Pharmaceutical care vs. Standard care was evaluated on Systolic blood pressure reduction from baseline to second follow-up (Mean difference 12.24 mmHg, p=0.0001). Pharmaceutical care provided by pharmacists significantly reduced systolic blood pressure by a mean difference of 12.24 mmHg compared to standard care in patients with essential hypertension.
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