Key result
D-dimer levels were significantly raised in all patients during the first week post-joint replacement, with no difference observed between patients with or without a proven DVT.
Why the study?
Does D-dimer testing accurately diagnose deep vein thrombosis in patients following total hip and knee replacement?
Population
78 patients following primary total hip and knee replacement who were ultrasonographically clear of DVT, and…
Comparison
D-dimer level measurement pre-operatively and… vs Age-matched group with proven DVT
Design
Cohort
Follow-up
7 days
Authors
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D-dimer elevation after joint replacement limits its diagnostic utility for DVT; leaves open the need for alternative biomarkers in prospective studies.
Observational (n=78)
Does D-dimer testing accurately diagnose deep vein thrombosis in patients following total hip and knee replacement?
D-dimer testing is not useful for diagnosing DVT following total hip and knee replacement as levels are universally elevated post-operatively, regardless of DVT status.
Rafee et al. (2008) conducted an observational in Deep vein thrombosis following total hip and knee replacement (n=78). D-dimer measurement vs. Age-matched group with proven DVT was evaluated on D-dimer levels. D-dimer levels were significantly raised in all patients during the first week post-joint replacement, with no difference observed between patients with or without a proven DVT.
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