Multivalidation analysis of the risk factors for ischemic heart disease and cerebral infarction.

Q: What does this research mean for the field?

Apolipoprotein ratios, particularly Apo A-I/Apo B and Apo A-I+A-II/Apo B, are highly effective markers for discriminating patients with ischemic heart disease and cerebral infarction from healthy individuals, whereas Apo B, total cholesterol, and LDL-cholesterol are effective for identifying myocardial infarction but not cerebral thrombosis. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Toshio Kawamoto; Hiroshi Sasaki; Itaru Horiuchi; Fumiaki Hino; Masami Ohki; Makoto OKAHASHI; Shôji Nishimura; Susumu Tazuma; Hironori Tokumo; Yoko Nomura; Toshihito Hiraoka; Masahiro Kawanishi; Tokuo Tsubokura; Goro Kajiyama

doi:10.3143/geriatrics.22.550

January 1, 1985Nippon Ronen Igakkai Zasshi Japanese Journal of GeriatricsOpen Access

Multivalidation analysis of the risk factors for ischemic heart disease and cerebral infarction.

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Why the study?

Are serum lipids, cholinesterase, and apolipoproteins effective in discriminating between patients with atherosclerotic diseases and healthy subjects?

Structured PICO

Are serum lipids, cholinesterase, and apolipoproteins effective in discriminating between patients with atherosclerotic diseases and healthy subjects?

P

Population

Patients with atherosclerotic diseases (old myocardial infarction, angina pectoris, cerebral thrombosis) and healthy subjects

I

Intervention

Measurement of serum lipids, cholinesterase (ChE), and apolipoproteins

C

Comparator

Healthy subjects

O

Outcome

Correct classification rate for discriminating between atherosclerotic diseases and healthy subjects using multivariate analysissurrogate

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Implication

Apolipoprotein measurements, particularly Apo A-I/Apo B ratios, are highly effective in discriminating between patients with cardiovascular or cerebrovascular atherosclerosis and healthy individuals.

Abstract

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Cite This Study

Kawamoto et al. (1985) studied this question.

synapsesocial.com/papers/6a18e9268dcaf40f45cfe6b8 https://doi.org/10.3143/geriatrics.22.550

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Multivalidation analysis of the risk factors for ischemic heart disease and cerebral infarction.

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Multivalidation analysis of the risk factors for ischemic heart disease and cerebral infarction.

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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