Key result
A critical review highlights the lack of uniform procedures and guidelines for selecting healthy reference populations and calculating the 99th percentile upper reference limit for cardiac troponin assays.
Design
Review
Authors
Loading...
Variability in troponin 99th percentile limits may affect MI diagnosis; leaves open need for international standardization guidelines.
There is a critical need for international consensus guidelines to standardize the selection of healthy reference populations and mathematical algorithms for calculating the 99th percentile upper reference limit for cardiac troponin assays.
Clerico et al. (2017) conducted a review in Myocardial Infarction. Cardiac troponin (cTn) 99th percentile upper reference limit evaluation was evaluated. A critical review highlights the lack of uniform procedures and guidelines for selecting healthy reference populations and calculating the 99th percentile upper reference limit for cardiac troponin assays.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: