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Objective. Myeloproliferative neoplasms (MPNs) are rare hematological malignancies characterized by debilitating fatigue. Chronic stimulation of the hypothalamicpituitary-adrenal axis, due to cytokine overproduction and other factors during the cancer process, may represent one of numerous pathways leading to fatigue and decreased quality of life. The purpose of this study was to explore the characteristics of the diurnal cortisol response of MPN cancer patients and examine its association with self-reported physical and mental health.
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Vizcaíno et al. (2018) studied this question.
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