Population
Human cardiac troponin T isoforms from normal adult, failing adult, and fetal human hearts
Design
Preclinical
Authors
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Fetal cTnT4 reexpression may mark failing myocardium; leaves open functional role or therapeutic targeting in human HF.
The study identifies the molecular basis of four human cardiac troponin T isoforms, revealing that the fetal isoform cTnT4 is reexpressed in the failing adult heart.
Anderson et al. (1995) studied this question.
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