Why the study?
Does acetylcholine induce vasoconstriction or vasodilation in human coronary arteries compared to other species?
Does acetylcholine induce vasoconstriction or vasodilation in human coronary arteries compared to other species?
Unlike in dogs, acetylcholine causes cholinergic vasoconstriction in human coronary arteries, highlighting important species differences with implications for coronary artery spasm.
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Acetylcholine constricts human coronaries unlike dogs; challenges consensus on endothelial responses and leaves open species-specific spasm mechanisms.
Stanley Kalsner (1985) studied this question.
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