Population
Atrial arterioles from human right atrial appendage and left ventricular vessels from explanted human hearts
Design
Preclinical
Authors
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Differential coronary endothelial responses may vary by atrial versus ventricular bed; animal data leaves open human translation and clinical relevance.
Isolated human coronary arterioles demonstrate endothelium-dependent dilation to various agonists, but exhibit a unique differential response to acetylcholine characterized by vasoconstriction in atrial vessels and dilation in ventricular arterioles.
Francis J. Miller (1998) studied this question.
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