What does this research mean for the field?

Clustered features of the metabolic syndrome are significantly and dose-dependently associated with an increased risk of developing aortic stiffness, as measured by increased aortic pulse wave velocity, in middle-aged men. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 1, 2003Angiology

Clustered Features of the Metabolic Syndrome and the Risk for Increased Aortic Pulse Wave Velocity in Middle-aged Japanese Men

View Full Paper

Ask AI

Bookmark

Why the study?

Does the clustering of metabolic syndrome features increase the risk of developing increased aortic pulse wave velocity in middle-aged men?

Population

2,431 Japanese men aged 35 to 54 years not taking antihypertensive medication, including a subset of 2,073…

Comparison

Presence of 1, 2, 3, or ≥4 features of metabolic… vs Subjects without any features of metabolic…

Design

Cohort

Follow-up

9 years

Authors

NNNoriyuki NakanishiTokyo University of Social Welfare KSKenji SuzukiMinistry of Health Labour and Welfare KTKozo TataraTokyo University of Social Welfare

Discussion

Member takes

Implication

Metabolic syndrome features were associated with dose-dependent aortic stiffness risk; extends observational data but leaves causal effects and interventions open.

Structured PICO

Does the clustering of metabolic syndrome features increase the risk of developing increased aortic pulse wave velocity in middle-aged men?

Population

2,431 Japanese men aged 35 to 54 years not taking antihypertensive medication (cross-sectional cohort), including a subset of 2,073 men without baseline aortic stiffness (PWV < 8.0 m/sec) for the longitudinal cohort.

Intervention

Presence of 1, 2, 3, or ≥4 features of metabolic syndrome (obesity, hypertension, hypercholesterolemia, low HDL, hypertriglyceridemia, high fasting plasma glucose, hyperuricemia)

Comparator

Subjects without any features of metabolic syndrome

Outcome

Increased aortic pulse wave velocity (PWV) of ≥ 8.0 m/secsurrogate

Clustered features of metabolic syndrome are prospectively associated with a dose-dependent increased risk of developing arterial stiffness (aortic PWV ≥ 8.0 m/sec) in middle-aged Japanese men.

Cite This Study

Nakanishi et al. (2003) studied this question.

synapsesocial.com/papers/6a199de71d4d911c80ea7154 https://doi.org/10.1177/000331970305400504

View Full Paper

Ask AI

Bookmark

Implication

Metabolic syndrome features were associated with dose-dependent aortic stiffness risk; extends observational data but leaves causal effects and interventions open.

Clustered Features of the Metabolic Syndrome and the Risk for Increased Aortic Pulse Wave Velocity in Middle-aged Japanese Men

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Clustered Features of the Metabolic Syndrome and the Risk for Increased Aortic Pulse Wave Velocity in Middle-aged Japanese Men

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider