Why the study?
Does propofol prevent QT interval prolongation compared to etomidate during electroconvulsive therapy in patients with major depression?
Population
14 unpremedicated American Society of Anesthesiologists I patients, each scheduled for 6 ECT sessions for…
Comparison
Propofol 1-mg/kg vs Etomidate 0.2-mg/kg
Design
RCT, randomized crossover
Follow-up
10 minutes after seizure ended
Authors
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Propofol warrants preference over etomidate for QTc management in ECT; extends randomized evidence guiding anesthetic choice in psychiatric care.
Does propofol prevent QT interval prolongation compared to etomidate during electroconvulsive therapy in patients with major depression?
Propofol provides better control of the QTc interval and hemodynamic response than etomidate during electroconvulsive therapy.
Erdil et al. (2009) studied this question.