Population
Mouse Kv1.4 voltage-gated K+ channel gene transcripts expressed in Xenopus oocytes
Comparison
3.5-kb transcript vs 4.5-kb transcript
Design
Preclinical
Authors
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Alternate Kv1.4 transcripts may modulate channel density in vivo; hypothesis-generating for post-transcriptional control in mammalian electrophysiology.
The functional expression of mouse Kv1.4 potassium channels is modulated by selective usage of alternate transcripts, with the shorter transcript producing significantly larger currents.
Wymore et al. (1996) studied this question.
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