Key result
A simplified ablation strategy using single transseptal puncture and contact force sensing achieved 85.0% freedom from atrial arrhythmia at 12 months in paroxysmal atrial fibrillation patients.
Why the study?
The study was conducted to evaluate the safety and efficacy of an optimized single transseptal puncture technique and contact force sensing radiofrequency catheter ablation strategy for paroxysmal AF.
Does a single transseptal puncture technique with contact force sensing catheter ablation provide safe and effective treatment in patients with paroxysmal atrial fibrillation?
Cohort (n=419)
No
Does a single transseptal puncture technique with contact force sensing catheter ablation provide safe and effective treatment in patients with paroxysmal atrial fibrillation?
A simplified single transseptal puncture technique with contact force sensing catheter ablation is a safe and effective approach for paroxysmal atrial fibrillation, achieving 85% sinus rhythm maintenance at 14.5 months.
May support simplified single-puncture ablation in paroxysmal AF; leaves open randomized comparison to standard techniques.
The present study aimed to evaluate the safety and efficacy of an optimized single transseptal puncture technique and contact force sensing atrial fibrillation (AF) radiofrequency catheter ablation (RFCA) strategy within a clinical setting. Fast anatomic mapping and contact force sensing ablation was applied to patients with paroxysmal AF (PAF) ablation between September 2014 and December 2016 using a single trans-septal sheath. Pulmonary vein isolation (PVI) and linear ablation were performed in PAF individually with a 10-20 g contact force with minimal fluoroscopy. Stimulation with 10 mA outputs on the lesions without capture was used as endpoint. A total of 419 consecutive patients who underwent first-time RFCA were enrolled in the current study, and acute PVI was achieved in all patients. The average procedure time was 74.5±9.7 min, with an average ablation time of 27.3±7.8 min. The average fluoroscopy time was 4.7±3.3 min and the average radiation dose was 24.3±25.2 mGy. At a mean follow-up time of 14.5 ± 4.1 months, sinus rhythm was maintained at 85.0%. Cardiac tamponade occurred in one case. The results indicated that this simplified technique was a simple, safe and effective approach for PAF ablation therapy.
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Du et al. (2020) conducted a cohort in Paroxysmal atrial fibrillation (n=419). Simplified ablation strategy (single transseptal puncture, fast anatomical mapping, contact force sensing, high output stimulation) was evaluated on Freedom from any documented episode of AF/AT sustained for >30 sec during the 12 month follow up outside a 3-month blanking period. A simplified ablation strategy using single transseptal puncture and contact force sensing achieved 85.0% freedom from atrial arrhythmia at 12 months in paroxysmal atrial fibrillation patients.
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