Why the study?
Does early treatment with captopril prevent short-term ventricular remodeling in patients with a first acute anterior myocardial infarction and elevated left filling pressures?
Population
68 patients with a first acute anterior myocardial infarction, including 40 patients with a pulmonary…
Comparison
Conventional therapy plus captopril vs Conventional therapy plus matching placebo
Design
RCT, randomized, double blind fashion
Follow-up
14 days
Authors
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Supports early captopril after anterior MI with elevated pressures; extends ACE inhibitor evidence to acute remodeling prevention.
Does early treatment with captopril prevent short-term ventricular remodeling in patients with a first acute anterior myocardial infarction and elevated left filling pressures?
Early administration of captopril in patients with a first acute anterior myocardial infarction and elevated filling pressures attenuates short-term ventricular enlargement.
Galcerá-Tomás et al. (1993) studied this question.
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