Why the study?
Does early vasodilator treatment with captopril or isosorbide mononitrate improve left ventricular size and function in patients with acute myocardial infarction?
Does early vasodilator treatment with captopril or isosorbide mononitrate improve left ventricular size and function in patients with acute myocardial infarction?
Early vasodilator treatment with captopril or isosorbide mononitrate did not improve left ventricular size or function in acute myocardial infarction patients, the majority of whom received thrombolysis.
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No benefit from early captopril or isosorbide mononitrate on post-MI LV remodeling; challenges prior benefits observed without thrombolysis.
Hargreaves et al. (1992) studied this question.
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