Key result
Endothelial dysfunction links to atherosclerosis and constitutes an intermediate step toward adverse CAD events.
Why the study?
Understanding the relation of endothelial function with CAD provides important pathophysiological insight useful in clinical and research management.
This review highlights the pathophysiological and prognostic role of endothelial dysfunction throughout the natural history of coronary artery disease.
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Endothelial dysfunction assessment may refine CAD risk stratification; leaves open whether targeting it alters outcomes in trials.
Gutiérrez et al. (2013) conducted a review in Coronary artery disease. Endothelial dysfunction is closely related to atherosclerosis and constitutes an intermediate step in the progression to adverse events throughout the natural history of coronary artery disease.
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