Why the study?
Does off-pump total arterial grafting improve medium-term mortality or readmission compared to conventional off-pump grafting with internal thoracic artery and saphenous vein grafts in patients undergoing multivessel CABG?
Does off-pump total arterial grafting improve medium-term mortality or readmission compared to conventional off-pump grafting with internal thoracic artery and saphenous vein grafts in patients undergoing multivessel CABG?
Off-pump total arterial grafting offers no medium-term mortality or morbidity benefits over conventional off-pump CABG using internal thoracic artery and saphenous vein grafts.
No medium-term outcome benefit seen with total arterial grafting; leaves open whether randomized trials would show superiority in multivessel off-pump CABG.
On-pump total arterial grafting is associated with improved long-term outcomes compared to conventional grafting using left internal thoracic artery and saphenous vein grafts, but there are no data to confirm the same for off-pump total arterial grafting. We assessed the impact of off-pump total arterial grafting on medium-term outcomes. From September 1998 to September 2008, 580 consecutive patients who had off-pump multivessel arterial grafting only were compared with a control group of 806 patients undergoing off-pump coronary artery bypass with internal thoracic artery and saphenous vein grafts, performed by the same surgeon. Perioperative data were collected prospectively. Medium-term univariate and risk-adjusted comparisons between the 2 groups were carried out. After adjusting for clinical covariates, total arterial grafting did not emerge as a significant independent predictor of medium-term mortality, readmission to hospital, or the composite outcome of death and readmission. At medium-term follow-up, off-pump total arterial grafting, despite being a safe and effective myocardial revascularization strategy, offered no mortality or morbidity benefits.
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Raja et al. (2010) studied this question.
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