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Digoxin protects the heart from the decrease in myocardial contractility during extended hypoxia, and this protective effect is significantly enhanced in the absence of autonomic function. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

August 1, 1975American Journal of Physiology-Legacy Content

Inotropic responses to digoxin during hypoxia and autonomic blockade

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KHKH Halloran SDSE Downing

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Implication

Digoxin augments ventricular contractility despite hypoxemia or blockade in dogs; leaves open translation to human hypoxemic states.

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Halloran et al. (1975) studied this question.

synapsesocial.com/papers/6a1a2f039b2d28adb7b4fa3b https://doi.org/10.1152/ajplegacy.1975.229.2.309

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Inotropic responses to digoxin during hypoxia and autonomic blockade

Discussion

Member takes

Implication

Key Points

Cite This Study

Inotropic responses to digoxin during hypoxia and autonomic blockade

Discussion

Member takes

Implication

Key Points

Cite This Study

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