Why the study?
Does dietary modification involving vitamin K intake cause anticoagulation instability in patients on long-term oral anticoagulants?
Does dietary modification involving vitamin K intake cause anticoagulation instability in patients on long-term oral anticoagulants?
Dietary modifications involving vitamin K intake must be undertaken with care in patients on long-term oral anticoagulants to prevent life-threatening complications.
Answers are grounded in this paper and cite their sources.
May warrant caution with vitamin K dietary changes in anticoagulated patients; case report leaves open prospective validation.
Anticoagulation instability due to a change in intake of vitamin K after dietary modification was observed in 2 patients on long-term oral anticoagulants. One patient developed diffuse bruises treated conservatively with fresh frozen plasma transfusion and the other had a thrombosed aortic prosthesis which required emergency operation. To prevent such complications, dietary modification especially with food rich in vitamin K should be undertaken with care in patients on long-term oral anticoagulants.
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Chow et al. (1990) studied this question.
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