Key result
Bilateral renal denervation reduces blood pressure in resistant hypertension, highlighting the role of afferent and efferent renal innervation in cardiovascular homeostasis and chronic renal disease.
Why the study?
Does bilateral renal denervation reduce blood pressure in patients with resistant hypertension?
Population
Patients with resistant hypertension, diabetes, obesity, and renal failure
Design
Review
Authors
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Hypothesis-generating for renal denervation in resistant hypertension; prospective RCTs required before practice change.
Does bilateral renal denervation reduce blood pressure in patients with resistant hypertension?
This review highlights the role of renal sensory afferent and efferent sympathetic nerves in cardiovascular homeostasis and the potential of renal denervation for treating resistant hypertension.
Edward J. Johns (2013) conducted a review in Hypertension and renal failure. Bilateral renal denervation was evaluated. Bilateral renal denervation reduces blood pressure in resistant hypertension, highlighting the role of afferent and efferent renal innervation in cardiovascular homeostasis and chronic renal disease.
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