Why the study?
Does captopril reduce blood pressure and urinary albumin excretion in outpatients with mild to moderate arterial hypertension, type 2 diabetes mellitus, and persistent macroalbuminuria?
Population
9 outpatients with mild to moderate arterial hypertension, type 2 diabetes mellitus and persistent…
Comparison
Captopril 50 mg twice a day for 6 months vs 1 month of placebo run-in prior to treatment
Design
Case_series
Follow-up
6 months
Authors
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Supports captopril for BP and macroalbuminuria control in diabetic hypertension; hypothesis-generating for preserved renal hemodynamics.
Does captopril reduce blood pressure and urinary albumin excretion in outpatients with mild to moderate arterial hypertension, type 2 diabetes mellitus, and persistent macroalbuminuria?
Captopril effectively lowers blood pressure and reduces macroalbuminuria in hypertensive diabetic patients without compromising renal hemodynamics or function.
Stornello et al. (1989) studied this question.
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