Key result
The presence of CAD or nonrevascularized myocardium in patients undergoing TAVI was not associated with differences in 1-year survival (overall 77.9%; P=0.63).
Why the study?
Does the presence and extent of coronary artery disease impact survival and clinical outcomes in patients undergoing TAVI?
Population
136 patients who underwent successful TAVI from January 2005 to December 2007
Comparison
TAVI in the presence of varying extents of… vs TAVI in patients with no coronary artery disease
Design
Cohort
Follow-up
1 year
Authors
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May support deferring routine revascularization in TAVI patients with CAD; leaves open need for RCTs to guide practice.
Cohort (n=136)
Does the presence and extent of coronary artery disease impact survival and clinical outcomes in patients undergoing TAVI?
p-value: p=0.63
The presence of coronary artery disease or nonrevascularized myocardium was not associated with an increased risk of adverse events up to 1 year after TAVI, suggesting complete revascularization may not be a prerequisite.
Masson et al. (2010) conducted a cohort in Transcatheter aortic valve implantation (TAVI) with or without coronary artery disease (n=136). Coronary artery disease (CAD) extent by Duke Myocardial Jeopardy Score vs. No CAD was evaluated on 30-day mortality and 1-year survival (p=0.63). The presence of CAD or nonrevascularized myocardium in patients undergoing TAVI was not associated with differences in 1-year survival (overall 77.9%; P=0.63).
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