Population
18 bilateral carotid arteries from 9 domestic crossbred swine subjected to severe mechanical crush injury
Comparison
Placement of a 3.5-mm Palmaz-Schatz stent… vs Crush injury alone in the contralateral artery
Design
Preclinical
Follow-up
1 hour
Authors
Loading...
Caution against extrapolating porcine findings to stent thrombosis management; leaves open platelets' mechanistic role in human acute closure.
In a porcine model of severe arterial injury, stent placement increased platelet deposition but improved vessel patency compared to crush injury alone, demonstrating that platelets are the primary component of acute stent thrombosis.
Jeong et al. (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: