What does this research mean for the field?

Maximum intensity plots based on 4D flow MRI velocity data provide an efficient method for measuring peak blood flow velocities in bicuspid aortic valve patients, offering higher accuracy than 2D phase contrast MRI and comparable accuracy to Doppler echocardiography. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to evaluate the effectiveness of maximum intensity plots from 4D flow MRI for assessing peak blood flow velocities in patients with bicuspid aortic valve.

May 18, 2016Journal of Magnetic Resonance Imaging

Efficient method for volumetric assessment of peak blood flow velocity using 4D flow MRI

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Why the study?

Does 4D flow MRI using maximum intensity plots accurately assess systolic peak velocities compared to 2D PCMRI and Doppler echocardiography in patients with bicuspid aortic valves?

Population

51 patients with bicuspid aortic valve (BAV)

Comparison

4D flow MRI at 1.5T using maximum intensity… vs 2D phase contrast MRI and Doppler echocardiography

Design

Cohort

Authors

MRMichael J. RoseThe University of Texas at Austin KJKelly JarvisNorthwestern University VCVarun ChowdharyNorthwestern University

Discussion

Member takes

Implication

May support 4D flow MRI for aortic velocity assessment in bicuspid valves; hypothesis-generating and requires prospective validation before practice change.

Key Points

This study aims to evaluate the effectiveness of maximum intensity plots from 4D flow MRI for assessing peak blood flow velocities in patients with bicuspid aortic valve.
Conducted 4D flow MRI on 51 bicuspid aortic valve patients using 1.5T equipment.
Generated maximum intensity plots from MRI data to measure velocities in three aortic regions.
Compared peak velocities from 4D flow MRI with 2D phase contrast MRI and Doppler echocardiography.
4D flow MRI peak velocities were significantly higher than 2D PCMRI (2.04 ± 0.71 m/s vs. 1.69 ± 0.79 m/s, P < 0.001).
Agreement between observers was excellent with a mean difference of 0.005 m/s and an intraclass correlation coefficient of 0.98.
4D flow MRI showed similar accuracy to Doppler echocardiography.

Structured PICO

Does 4D flow MRI using maximum intensity plots accurately assess systolic peak velocities compared to 2D PCMRI and Doppler echocardiography in patients with bicuspid aortic valves?

Population

51 patients with bicuspid aortic valve (BAV)

Intervention

4D flow MRI at 1.5T using maximum intensity plots (MIPs) to determine peak velocities

Comparator

2D phase contrast MRI (2D PCMRI) (n=36) and Doppler echocardiography (n=34)

Outcome

Systolic peak velocities in the ascending aorta, aortic arch, and descending aorta, and interobserver variabilitysurrogate

4D flow MRI using maximum intensity plots is an efficient and accurate method for measuring peak velocities in bicuspid aortic valve patients, yielding higher velocities than 2D PCMRI and similar to Doppler echocardiography.

Cite This Study

Rose et al. (2016) studied this question.

synapsesocial.com/papers/6a1bc4b2c97d63156a5ee67a https://doi.org/10.1002/jmri.25305

Topics

Valvular heart disease

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Implication

May support 4D flow MRI for aortic velocity assessment in bicuspid valves; hypothesis-generating and requires prospective validation before practice change.

Efficient method for volumetric assessment of peak blood flow velocity using 4D flow MRI

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Efficient method for volumetric assessment of peak blood flow velocity using 4D flow MRI

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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