Key result
Bicuspid aortic valves have ~8% higher average peak velocity than tricuspid valves despite similar dimensions.
Why the study?
Does 4D flow MRI identify morphological and hemodynamic differences between patients with bicuspid aortic valves, tricuspid aortic valves with dilated aortas, and healthy controls?
Cross-Sectional (n=165)
Does 4D flow MRI identify morphological and hemodynamic differences between patients with bicuspid aortic valves, tricuspid aortic valves with dilated aortas, and healthy controls?
Absolute Event Rate: 1.3% vs 1.2%
p-value: p=<0.016
4D flow MRI demonstrates that patients with bicuspid aortic valves have altered aortic hemodynamics compared to those with tricuspid aortic valves, even when aortic dimensions are similar.
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May warrant caution against relying solely on aortic dimensions in bicuspid valves; leaves open 4D flow MRI's prognostic utility.
García et al. (2015) conducted a cross-sectional in Bicuspid aortic valve and dilated aorta (n=165). 4D flow MRI vs. Tricuspid aortic valve and controls was evaluated on Average peak velocity between the left ventricle outflow tract to sino-tubular junction (p=<0.016). Four-dimensional flow MRI demonstrated that patients with bicuspid aortic valves had higher average peak velocity (1.3 vs 1.2 m/s; P<0.016) compared to tricuspid valves despite similar dimensions.
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