Why the study?
Do vascular risk factors predict the incidence of late-life depression in older adults?
Population
661 community participants aged 65 years or over, without depression at baseline
Comparison
Vascular risk factors vs Absence of these vascular risk factors
Design
Cohort
Follow-up
2 years
Authors
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Should not yet change depression prevention practice; leaves open whether modifying vascular risks reduces late-life depression incidence.
Do vascular risk factors predict the incidence of late-life depression in older adults?
Pre-existing heart disease, incident stroke, and lower HDL cholesterol are independent predictors of incident late-life depression, supporting a vascular etiology.
Kim et al. (2006) studied this question.
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