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August 1, 1995Magnetic Resonance in Medicine

Quantitative analysis of regional left ventricular function after myocardial infarction in the pig assessed with cine magnetic resonance imaging

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Why the study?

Does quantitative analysis of cine MR images accurately determine localization and extent of regional left ventricular dysfunction in an infarcted pig heart model compared to Gd-DTPA-enhanced spin-echo MR imaging and pathology?

Population

8 pigs before and after myocardial infarction

Comparison

Quantitative analysis of global and regional… vs Gadolinium diethylenetriaminepentaacetic…

Design

Preclinical

Authors

EHEduard R. HolmanCardiac ImagingHVHubert W. VliegenAdult Congenital Heart DiseaseRGRob J. Der Van GeestLeiden University

Discussion

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Implication

Supports cine MR infarct localization in pigs; leaves open human validation.

Structured PICO

Does quantitative analysis of cine MR images accurately determine localization and extent of regional left ventricular dysfunction in an infarcted pig heart model compared to Gd-DTPA-enhanced spin-echo MR imaging and pathology?

P
Population
8 pigs before and after myocardial infarction
I
Intervention
Quantitative analysis of global and regional wall motion and wall thickening of the left ventricle with cine magnetic resonance (MR) imaging using the centerline method
C
Comparator
Gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA)-enhanced multislice spin-echo MR imaging and determination of pathology
O
Outcome
Accuracy of quantitative analysis of global and regional wall motion and wall thickening of the left ventriclesurrogate

Quantitative analysis of cine MR images using the centerline method accurately localizes and assesses the extent of regional left ventricular dysfunction in a pig model of myocardial infarction.

Cite This Study

Holman et al. (1995) studied this question.

synapsesocial.com/papers/6a1bca3dd54006be995efc2dhttps://doi.org/10.1002/mrm.1910340206

Topics

Cardiac MRI
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Assessment of regional left ventricular function by magnetic resonance.1986 · 72 citations
  2. 2Multiphasic cardiac magnetic resonance imaging: normal regional left ventricular wall thickening1985 · 86 citations
  3. 3Quantification and validation of left ventricular wall thickening by a three-dimensional volume element magnetic resonance imaging approach.1990 · 107 citations
  4. 4The multicentric character of normal left ventricular wall motion. Implications for the evaluation of regional wall motion abnormalities by contrast angiography1982 · 15 citations
  5. 5Development of an improved centreline wall motion model2002 · 11 citations