Long-term histologic examination of cryoablation lesions demonstrates sharply demarcated, homogeneous fibrous scars that lack arrhythmogenic potential.
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May support long-term cryoablation safety; hypothesis-generating pending larger histologic series.
This report describes cardiac morphologic alterations in a patient who died 14 months following cryoablation. Histologic examination of the long-term cryolesion revealed a homogeneous fibrous scar with surrounding sinusoid capillary proliferation. The border between the fibrosis and the normal myocardium was sharply defined. Cryothermia is an excellent technique for the surgical correction of arrhythmias because it provides sharply demarcated lesions which lack arrhythmogenic potential.
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Watanabe et al. (1996) studied this question.
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