What does this research mean for the field?

Natural baroreceptor stimulation during systole reduces nociceptive responding, and artificial baroreceptor inhibition reduces pain ratings, providing partial support for baroreflex modulation of pain. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

August 4, 2003Psychophysiology

Effects of artificial and natural baroreceptor stimulation on nociceptive responding and pain

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Why the study?

Does artificial and natural baroreceptor stimulation affect nociceptive responding and pain in normotensive adults?

Population

25 normotensive adults

Comparison

Brief neck suction and neck compression combined… vs No pressure and diastole

Design

Other

Authors

LELouisa EdwardsUniversity of British Columbia Hospital DMDavid McIntyreQueen's University Belfast DCDouglas CarrollRutgers, The State University of New Jersey

Discussion

Member takes

Implication

Baroreceptor effects on pain vary by stimulation method; leaves open baroreflex mediation of hypertensive hypoalgesia pending higher-level trials.

Structured PICO

Does artificial and natural baroreceptor stimulation affect nociceptive responding and pain in normotensive adults?

Population

25 normotensive adults

Intervention

Brief neck suction (artificial baroreceptor stimulation) and neck compression (baroreceptor inhibition) combined with sural nerve electrocutaneous stimulation during systole or diastole

Comparator

No pressure (for artificial stimulation) and diastole (for natural stimulation)

Outcome

Nociceptive responding (indexed by electromyographic activity elicited in the biceps femoris) and pain ratings (intensity of sural stimulation)patient reported

The study provides partial support for baroreflex modulation of pain, demonstrating differential effects of natural versus artificial baroreceptor stimulation on nociceptive responding and pain ratings.

Cite This Study

Edwards et al. (2003) studied this question.

synapsesocial.com/papers/6a1bd1ec0a1f7575939cfe33 https://doi.org/10.1111/1469-8986.00076

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Implication

Baroreceptor effects on pain vary by stimulation method; leaves open baroreflex mediation of hypertensive hypoalgesia pending higher-level trials.

Effects of artificial and natural baroreceptor stimulation on nociceptive responding and pain

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Effects of artificial and natural baroreceptor stimulation on nociceptive responding and pain

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider