Why the study?
Does the comorbidity of obesity and essential arterial hypertension increase the frequency of diastolic dysfunction and left ventricular remodeling in patients with type II diabetes mellitus?
Does the comorbidity of obesity and essential arterial hypertension increase the frequency of diastolic dysfunction and left ventricular remodeling in patients with type II diabetes mellitus?
Comorbid arterial hypertension and obesity in patients with type II diabetes are associated with increased left ventricular remodeling and diastolic dysfunction, potentially accelerating the development of heart failure.
May support closer LV monitoring in comorbid diabetes; leaves open whether BP control alters progression to HF.
Aim. To study of obesity and essential arterial hypertension on development of diastolic dysfunctions and remodeling of left ventricular in patients with type II diabetes mellitus without coronary heart disease. Material and мethods. The echocardiography with estimation of diastolic properties and diagnostics remodeling of left ventricular in 134 patients with type II diabetes aged 26 to 66 years has been investigated. Results. The greatest contribution to development of diastolic dysfunctions and remodeling of left ventricular at combination of obesity and arterial hypertension with type II diabetes brings increase of arterial pressure. The increase in degree of obesity in patients with type II diabetes and arterial hypertension promotes more often development of concentric hypertrophy of myocardium of left ventricular. Conclusion. Comorbidity of arterial hypertension and adiposity in patients with type II diabetes mellitus are accompanied with increase in frequency of diastolic dysfunctions and remodeling of myocardium left ventricular that can promote fast development of heart failure.
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Koroleva et al. (2014) studied this question.
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