Why the study?
Are plasma atrial natriuretic factor (ANF) concentrations elevated in untreated essential hypertension and what are their clinical correlates?
Population
Normotensive subjects and subjects with untreated, uncomplicated essential hypertension
Design
Cross-sectional
Authors
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ANF elevation associates with hypertension severity; leaves open causal role and clinical utility pending prospective studies.
Are plasma atrial natriuretic factor (ANF) concentrations elevated in untreated essential hypertension and what are their clinical correlates?
Plasma ANF is elevated in untreated essential hypertension and correlates with arterial pressure in hypertensive but not normotensive individuals.
Montorsi et al. (1987) studied this question.
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