Why the study?
Does an accelerated infusion of streptokinase improve reperfusion rates and clinical outcomes in patients with a first episode of acute STEMI?
Population
300 patients with their first episode of acute ST-elevation myocardial infarction, mean age 59 ± 12 years…
Comparison
Accelerated infusion of streptokinase vs Conventional infusion of streptokinase
Design
RCT, randomized, double blind
Follow-up
1 year
Authors
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Accelerated streptokinase warrants consideration in STEMI; confirms randomized benefit on reperfusion versus standard infusion.
Does an accelerated infusion of streptokinase improve reperfusion rates and clinical outcomes in patients with a first episode of acute STEMI?
An accelerated 20-minute infusion of streptokinase significantly improves reperfusion rates, preserves left ventricular function, and reduces mortality compared to the standard 60-minute infusion in acute STEMI.
Ghaffari et al. (2011) studied this question.
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