Why the study?
The study was conducted to substantiate the feasibility of combination antihypertensive therapy in patients with arterial hypertension without target organ damage and high cardiovascular risk.
Does a fixed-dose combination of amlodipine and losartan improve blood pressure control and daily profile in a patient with hypertension, dyslipidemia, and obesity?
Does a fixed-dose combination of amlodipine and losartan improve blood pressure control and daily profile in a patient with hypertension, dyslipidemia, and obesity?
A fixed-dose combination of amlodipine and losartan successfully achieved target blood pressure and improved the diurnal blood pressure profile in a high-risk hypertensive patient.
The article substantiates the feasibility of combination antihypertensive therapy in patients with arterial hypertension without target organ damage and high cardiovascular risk. The authors consider a clinical case of the use of amlodipine and losartan in a fixed-dose combination (Lozap AM) as part of complex therapy in a patient with arterial hypertension, dyslipidemia and obesity. The clinical case showed the ability of the drug to both achieve a steady level of target blood pressure and improve its daily profile by transferring the Night-peaker type to the Non-dipper type.
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В. П. Михин (2020) studied this question.
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