Why the study?
Do selective or low-lipophilicity β-blockers reduce the risk of insomnia compared to non-selective or high-lipophilicity β-blockers in elderly patients with newly diagnosed hypertension?
Population
4,063 patients aged above 65 years with newly diagnosed hypertension treated with β-blockers, based in Taiwan
Comparison
Bisoprolol, atenolol, selective β-blockers, or… vs Propranolol, non-selective β-blockers, or…
Design
Cohort
Follow-up
1 year
Authors
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May support preferring bisoprolol or atenolol over propranolol to lower insomnia risk in elderly hypertension; leaves open need for RCTs.
Do selective or low-lipophilicity β-blockers reduce the risk of insomnia compared to non-selective or high-lipophilicity β-blockers in elderly patients with newly diagnosed hypertension?
In elderly patients with newly diagnosed hypertension, the use of selective or low-lipophilicity β-blockers like bisoprolol and atenolol is associated with a significantly lower risk of insomnia compared to propranolol.
Chang et al. (2012) studied this question.
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