What does this research mean for the field?

Altered myogenic responsiveness of the renal microvasculature, particularly in the afferent arterioles and interlobular arteries, is a pivotal determinant of renal autoregulation and plays a crucial role in protecting glomeruli from barotrauma in experimental hypertension. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

December 1, 1996Journal of Hypertension

Altered myogenic responsiveness of the renal microvasculature in experimental hypertension

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Population

Experimental hypertension models including spontaneously hypertensive rats, Dahl salt-sensitive rats…

Design

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Authors

KHKôichi HayashiSt. Marianna University School of Medicine MEMurray EpsteinUniversity of Miami TSTakao SarutaNorthwestern University

Discussion

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Implication

Altered myogenic tone may reset renal autoregulation in experimental hypertension; hypothesis-generating for human glomerular protection strategies.

Structured PICO

Population

Experimental hypertension models including spontaneously hypertensive rats (SHR), Dahl salt-sensitive rats, Goldblatt renal hypertensive rats, and normotensive Wistar-Kyoto rats (WKY)

Outcome

Renal microvascular responsiveness to pressuresurrogate

Altered myogenic preglomerular tone in experimental hypertension plays a pivotal role in resetting renal autoregulation and protecting glomeruli from barotrauma.

Cite This Study

Hayashi et al. (1996) studied this question.

synapsesocial.com/papers/6a1c10801567d2fc4d5f8849 https://doi.org/10.1097/00004872-199612000-00002

Topics

Hypertension management

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Implication

Altered myogenic tone may reset renal autoregulation in experimental hypertension; hypothesis-generating for human glomerular protection strategies.

Altered myogenic responsiveness of the renal microvasculature in experimental hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Altered myogenic responsiveness of the renal microvasculature in experimental hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

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