Key result
Apical hypertrophic cardiomyopathy can mimic acute myocardial infarction with abrupt ST-elevation despite normal coronaries.
Why the study?
Apical ischemia is relevant in the pathophysiology of apical hypertrophic cardiomyopathy and could explain chest pain and dynamic ST-segment changes simulating acute coronary syndrome.
Case Report (n=1)
Apical hypertrophic cardiomyopathy can present with severe transmural ischemia mimicking ST-segment elevation myocardial infarction despite normal coronary arteries.
Answers are grounded in this paper and cite their sources.
Clinicians should consider apical HCM in STEMI mimics with normal coronaries; single-case observation leaves prevalence and mechanisms open.
Recent studies demonstrate the relevance of apical ischemia in the pathophysiology of apical hypertrophic cardiomyopathy. This finding could explain why some patients may exhibit chest pain and dynamic ST-segment changes simulating an acute coronary syndrome. We present a paradigmatic case of apical hypertrophic cardiomyopathy with normal coronary arteries presenting with prolonged chest pain and ST-segment elevation myocardial infarction.
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López-Ibor et al. (2025) conducted a case report in Apical hypertrophic cardiomyopathy (n=1). Apical hypertrophic cardiomyopathy was evaluated on Clinical presentation and ECG findings. Patients with apical hypertrophic cardiomyopathy may present with abrupt ST-segment elevation and chest pain mimicking an acute myocardial infarction despite normal coronary arteries.
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